|
KMID : 1123920060200030657
|
|
Korean Journal of Oriental Physiology and Pathology
2006 Volume.20 No. 3 p.657 ~ p.662
|
|
|
Effects of the Combined-administration of Acanthopanacis Cortex and Lycii Cortex Radicis on Immune Response
|
|
Eun Jae-Soon
Lee Kyung-A
Park Hoon
Kwon Jin
|
|
|
Abstract
|
|
|
|
Immunological activities of the combined-administration of Acanthopanacis Cortex and Lycii Cortex Radicis were examined in BALB/C mice. The 40% ethyl alcohol extract of Acanthopanacis Corter (AE) or the 40% ethyl alcohol extract of Acanthopanacis Coriex and Lycii Cortex Radicis (ALE) were administered p.o. once a day for 7 days, respectively. AE did not affect the viability of thymocytes, but ALE decreased the viability of thymocytes. ALE enhanced the viability of splenocytes increased by AE. Also, AE enhanced the population of cytotoxic T cell in thymocytes, and ALE enhanced the population of helper T cell compared with AE. Furthermore, AE increased the population of cells in splenocytes, and increased the population of splenic cells. In addition, ALE enhanced the phagocytic activity which was decreased by AE ALE decreased the production of nitric oxide increased by AE in peritoneal macrophages. These results suggest that ALE enhance an immune-regulative action of AE.
|
|
|
KEYWORD
|
|
|
Acanthopanacis Cortex, Lycii Cortex Radicis, thymocytes, splenocytes, phagocytic activity, nitric oxide
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|